National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting, 30431-30432 [06-4890]

Download as PDF jlentini on PROD1PC65 with NOTICES Federal Register / Vol. 71, No. 102 / Friday, May 26, 2006 / Notices pharmacologic agent known to influence p21 expression, the synthetic triterpenoid and peroxisome proliferator-activated receptor gamma (PPARg) ligand, 2-cyano-3,12dioxooleana-1,9-dien-28-oic acid (CDDO) or its derivative di-CDDO, was shown to moderate virally-induced p21 expression and concurrently dampen HIV infection. CDDO is part of a class of synthetic triterpenoids based on natural products resembling steroids in their biogenesis and in their pleiotropic actions. A newly developed CDDO derivative, which is orally bioavailable, also suppresses HIV. These results, coupled with the evidence that macrophage p21 is a requisite macrophage facilitator of viral replication, intensify the interest to further develop these compounds as antiretroviral agents. The anti-retroviral effect of CDDO was evident when peripheral blood mononuclear cells (PBMC) were infected with a T-tropic (X4) or dual tropic viral (R5X4) strain of HIV–1. These studies suggest that these triterpenoids may aid in the control of retroviral replication. Neither p21 oligonucleotides nor CDDO were toxic to the cultured macrophages or peripheral blood mononuclear cells. Thus, p21 inhibitors could be safe and effective anti-HIV therapeutic candidates to be used independently and/or in conjunction with current antiretroviral therapy. In this regard, CDDO will be entered into human trials for the first time in the near future for its anticancer indications, thereby determining its maximally tolerated dose for use in subsequent HIV/AIDS clinical trials. Current anti-retroviral therapy, often characterized by high toxicity and the emergence of drug resistant virus strains, may be augmented through the identification of these and other new anti-viral agents targeting host cellular molecules less prone to mutational events. Inventors: Sharon M. Wahl, Nancy Vazquez-Maldonado, Teresa GreenwellWild (NIDCR). Publications: 1. S.M. Wahl et al., ‘‘HIV accomplices and adversaries in macrophage infection,’’ J. Leukoc. Biol. 2006, in press. 2. N. Vazquez et al., ‘‘Human immunodeficiency virus type 1-induced macrophage gene expression includes the p21 gene, a target for viral regulation,’’ J. Virol. (2005 Apr) 79(7):4479–4491. Patent Status: U.S. Provisional Application No. 60/516,794 filed November 4, 2003 (HHS Reference No. E–114–2003/0–US–01); PCT Application No. PCT/US2004/36492 VerDate Aug<31>2005 16:12 May 25, 2006 Jkt 208001 filed November 3, 2004, which published as WO 2005/046732 on May 26, 2005 (HHS Reference No. E–114– 2003/0–PCT–02) Licensing Status: Available for nonexclusive or exclusive licensing. Licensing Contact: Sally Hu, PhD., M.B.A.; 301/435–5606; hus@mail.nih.gov Collaborative Research Opportunity: The National Institute of Dental and Craniofacial Research, Oral Infection and Immunity Branch, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact David W. Bradley, PhD., at bradleyda@nidcr.nih.gov or by phone at 301/402–0540 for more information. Dated: May 18, 2006. David R. Sadowski, Acting Director, Division of Technology Development and Transfer, Office of Technology Transfer, National Institutes of Health. [FR Doc. E6–8176 Filed 5–25–06; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health 30431 Date: June 13, 2006. Closed: 8:30 a.m. to 10 a.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Two Democracy Plaza, 6707 Democracy Boulevard, Suite 800, Bethesda, MD 20892. Open: 10 a.m. to 5 p.m. Agenda: The agenda will include Opening Remarks, Administrative Matters, Director’s Report, NCMHD, IC Strategic Plan Report, NIH Minority Research Training Programs Update, NCMHD Program Highlights, and other business of the Council. Place: National Institutes of Health, Two Democracy Plaza, 6707 Democracy Boulevard, Suite 800, Bethesda, MD 20892. Contact Person: Donna Brooks, Asst. Director for Administration, National Center on Minority Health and Health Disparities, National Institutes of Health, 6707 Democracy Blvd., Suite 800, Bethesda, MD 20892. 301–435–2135. brooksd@ncmhd.nih.gov. Any interested person may file written comments with the committee by forwarding the statement to the Contact Person listed on this notice. The statement should include the name, address, telephone number and when applicable, the business or professional affiliation of the interested person. Dated: May 18, 2006. Anna Snouffer, Acting Director, Office of the Federal Advisory Committee Policy. [FR Doc. 06–4893 Filed 5–25–06; 8:45 am] BILLING CODE 4140–01–M National Center on Minority Health and Health Disparities; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of a meeting of the National Advisory Council on Minority Health and Health Disparities. The meeting will be open to the public as indicated below, with attendance limited to space available. Individuals who plan to attend and need special assistance, such as sign language interpretation or other reasonable accommodations, should notify the Contact Person listed below in advance of the meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Advisory Council on Minority Health and Health Disparities. PO 00000 Frm 00067 Fmt 4703 Sfmt 4703 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Allergy, Immunology, and Transplantation Research Committee, Allergy, Immunology and Transplantation Research Committee (AITRC). Date: June 12, 2006. Time: 8 a.m. to 5 p.m. E:\FR\FM\26MYN1.SGM 26MYN1 30432 Federal Register / Vol. 71, No. 102 / Friday, May 26, 2006 / Notices Agenda: To review and evaluate grant applications. Place: Double Tree Rockville, 1750 Rockville Pike, Rockville, MD 20852. Contact Person: Mercy R. PrabhuDas, PhD., Scientific Review Administrator, Scientific Review Program, Division of Extramural Activities, National Institutes of Health/ NIAID, 6700B Rockledge Drive, MSC 7616, Bethesda, MD 20892–7616. 301–451–2615. mp457n@nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.855, Allergy, Immunology, and Transplantation Research; 93.856, Microbiology and Infectious Diseases Research, National Institutes of Health, HHS) Dated: May 18, 2006. Anna Snouffer, Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–4890 Filed 5–25–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Dental & Craniofacial Research; Notice of Closed Meetings jlentini on PROD1PC65 with NOTICES Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel, 06–82, Review R21s. Date: June 19, 2006. Time: 10 a.m. to 12 p.m. Agenda: To review and evaluate grant applications Place: National Institutes of Health, Natcher Building, 45 Center Drive, Bethesda, MD 20892. (Telephone Conference Call). Contact Person: Sooyoun (Sonia) Kim, MS, Associate SRA, 45 Center Dr, 4An 32B, Division of Extramural Research, National Inst. of Dental & Craniofacial Research, National Institute of Health, Bethesda, MD 20892. (301) 594–4827. kims@email.nidr.nih.gov. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel, 06–93, Review F30, F32, R03. VerDate Aug<31>2005 16:12 May 25, 2006 Jkt 208001 Date: June 20, 2006. Time: 1:30 p.m. to 3 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Natcher Building, 45 Center Drive, Bethesda, MD 20892. (Telephone Conference Call). Contact Person: Rai K. Krishnaraju, PhD., MS, Scientific Review Administrator, Scientific Review Branch, National Inst. of Dental & Craniofacial Research, National Institutes of Health, 45 Center Dr., Rm. 4An 32J, Bethesda, MD 20892. 301–594–4864. kkrishna@nidcr.nih.gov. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel, 06–77, Review R01. Date: June 20, 2006. Time: 3 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Natcher Building, 45 Center Drive, Bethesda, MD 20892. (Telephone Conference Call). Contact Person: Sooyoun (Sonia) Kim, MS, Associate SRA, 45 Center Dr., 4An 32B, Division of Extramural Research, National Inst. of Dental & Craniofacial Research, National Institue of Health, Bethesda, MD 20892. (301) 594–4827. kims@email.nidr.nih.gov. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel, 06–76, Review R01. Date: July 13, 2006. Time: 12 p.m. to 2 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Natcher Building, 45 Center Drive, Bethesda, MD 20892. (Telephone Conference Call). Contact Person: Sooyoun (Sonia) Kim, MS, Associate SRA, 45 Center Dr., 4An 32B, Division of Extramural Research, National Inst. of Dental & Craniofacial Research, National Institute of Health, Bethesda, MD 20892. (301) 594–4827. kims@email.nidr.nih.gov. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel, 06–84, Review R21. Date: July 19, 2006. Time: 2 p.m. to 3 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Natcher Building, 45 Center Drive, Bethesda, MD 20892 (Telephone Conference Call). Contact Person: Sooyoun (Sonia) Kim, MS, Associate SRA, 45 Center Dr., 4An 32B, Division of Extramural Research, National Inst. of Dental & Craniofacial Research, National Institute of Health, Bethesda, MD 20892. (301) 594–4827. kims@email.nidr.nih.gov. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel, 06–92, Review R03. Date: August 4, 2006. Time: 11 a.m. to 12 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Natcher Building, 45 Center Drive, Bethesda, MD 20892 (Telephone Conference Call). PO 00000 Frm 00068 Fmt 4703 Sfmt 4703 Contact Person: Mary Kelly, Scientific Review Specialist, National Institute of Dental & Crainofacial Res., 45 Center Drive, Natcher Bldg., Rm. 4AN38J, Bethesda, MD 20892–6402. (301) 594–4809. mary_kelly@nih.gov. (Catalgoue of Federal Domestic Assistance Program Nos. 93.121, Oral Diseases and Disorders Research, National Institutes of Health, HHS) Dated: May 18, 2006. Anna Snouffer, Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–4891 Filed 5–25–06; 8:45 am] BILLING CODE 4140–01–M DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institutes of Deafness and Other Communication Disorders; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. Appendix 2), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Communication Disorders Review Committee. Date: June 21–22, 2006. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Wyndham Washington, DC, 1400 M Street, NW., Washington, DC 20005. Contact Person: Melissa J. Stick, PhD., MPH, Chief, Scientific Review Branch, Scientific Review Branch, Division of Extramural Research, NIDCD/NIH, 6120 Executive Blvd., Bethesda, MD 20892. 301– 496–8683. (Catalogue of Federal Domestic Assistance Program Nos. 93.173, Biological Research Related to Deafness and Communicative Disorders, National Institutes of Health, HHS) Dated: May 18, 2006. Anna Snouffer, Acting Director, Office of Federal Advisory Committee Policy. [FR Doc. 06–4892 Filed 5–25–06; 8:45am] BILLING CODE 4140–01–M E:\FR\FM\26MYN1.SGM 26MYN1

Agencies

[Federal Register Volume 71, Number 102 (Friday, May 26, 2006)]
[Notices]
[Pages 30431-30432]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 06-4890]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Institute of Allergy and Infectious Diseases; Notice of 
Closed Meeting

    Pursuant to section 10(d) of the Federal Advisory Committee Act, as 
amended (5 U.S.C. Appendix 2), notice is hereby given of the following 
meeting.
    The meeting will be closed to the public in accordance with the 
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 
U.S.C., as amended. The grant applications and the discussions could 
disclose confidential trade secrets or commercial property such as 
patentable material, and personal information concerning individuals 
associated with the grant applications, the disclosure of which would 
constitute a clearly unwarranted invasion of personal privacy.

    Name of Committee: Allergy, Immunology, and Transplantation 
Research Committee, Allergy, Immunology and Transplantation Research 
Committee (AITRC).
    Date: June 12, 2006.
    Time: 8 a.m. to 5 p.m.

[[Page 30432]]

    Agenda: To review and evaluate grant applications.
    Place: Double Tree Rockville, 1750 Rockville Pike, Rockville, MD 
20852.
    Contact Person: Mercy R. PrabhuDas, PhD., Scientific Review 
Administrator, Scientific Review Program, Division of Extramural 
Activities, National Institutes of Health/NIAID, 6700B Rockledge 
Drive, MSC 7616, Bethesda, MD 20892-7616. 301-451-2615. 
mp457n@nih.gov.

(Catalogue of Federal Domestic Assistance Program Nos. 93.855, 
Allergy, Immunology, and Transplantation Research; 93.856, 
Microbiology and Infectious Diseases Research, National Institutes 
of Health, HHS)

    Dated: May 18, 2006.
Anna Snouffer,
Acting Director, Office of Federal Advisory Committee Policy.
[FR Doc. 06-4890 Filed 5-25-06; 8:45 am]
BILLING CODE 4140-01-M

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