Use of Diagnostic Code Numbers; Schedule of Ratings-Neurological Conditions and Convulsive Disorders, 75398-75399 [05-24272]
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75398
Federal Register / Vol. 70, No. 243 / Tuesday, December 20, 2005 / Rules and Regulations
Food and Drug Administration
21 CFR Parts 510 and 520
New Animal Drugs; Change of
Sponsor; Chloramphenicol Capsules
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Final rule.
The Food and Drug
Administration (FDA) is amending the
animal drug regulations to reflect a
change of sponsor for a new animal drug
application (NADA) for
chloramphenicol capsules from Nylos
Trading Co., Inc., to Pharmaceutical
Ventures, Ltd.
DATES: This rule is effective December
20, 2005.
FOR FURTHER INFORMATION CONTACT:
David R. Newkirk, Center for Veterinary
Medicine (HFV–100), Food and Drug
Administration, 7500 Standish Pl.,
Rockville, MD 20855, 301–827–6967, email: david.newkirk@fda.gov.
SUPPLEMENTARY INFORMATION: Nylos
Trading Co., Inc., P.O. Box 2, Route 202,
Pomona, NY 10970, has informed FDA
that it has transferred ownership of, and
all rights and interest in, NADA 65–150
for Chloramphenicol Capsules to
Pharmaceutical Ventures, Ltd., P.O. Box
D1400, Pomona, NY 10970.
Accordingly, the regulations are
amended in § 520.390b (21 CFR
520.390b) to reflect this change of
sponsorship and a current format. In
addition, FDA is taking this opportunity
to revise § 520.390b to reflect the
prohibition of extralabel use of
chloramphenicol in food-producing
animals under 21 CFR 530.41.
Following these changes of
sponsorship, Nylos Trading Co., Inc., is
no longer the sponsor of an approved
application. Accordingly, 21 CFR
510.600(c) is being amended to remove
the entries for Nylos Trading Co., Inc.
This rule does not meet the definition
of ‘‘rule’’ in 5 U.S.C. 804(3)(A) because
it is a rule of ‘‘particular applicability.’’
Therefore, it is not subject to the
congressional review requirements in 5
U.S.C. 801–808.
SUMMARY:
21 CFR Part 510
Administrative practice and
procedure, Animal drugs, Labeling,
Reporting and recordkeeping
requirements.
21 CFR Part 520
Animal drugs.
16:09 Dec 19, 2005
PART 510—NEW ANIMAL DRUGS
1. The authority citation for 21 CFR
part 510 continues to read as follows:
I
Authority: 21 U.S.C. 321, 331, 351, 352,
353, 360b, 371, 379e.
2. Section 510.600 is amended in the
table in paragraph (c)(1) by removing
the entry for ‘‘Nylos Trading Co., Inc.’’
and by alphabetically adding a new
entry for ‘‘Pharmaceutical Ventures,
Ltd.’’; and in the table in paragraph
(c)(2) by removing the entry for
‘‘027454’’ and by numerically adding a
new entry for ‘‘050057’’ to read as
follows:
I
Jkt 208001
(2) No. 058034 for capsules containing
100 or 250 mg chloramphenicol.
(c) Special considerations. Federal
law prohibits the extralabel use of this
product in food-producing animals.
(d) Conditions of use in dogs—(1)
Amount. 25 mg per pound of body
weight every 6 hours.
(2) Indications for use. For treatment
of bacterial pulmonary infections,
bacterial infections of the urinary tract,
bacterial enteritis, and bacterial
infections associated with canine
distemper caused by susceptible
organisms.
(3) Limitations. Federal law restricts
this drug to use by or on the order of
a licensed veterinarian.
Dated: December 8, 2005.
Bernadette A. Dunham,
Deputy Director, Office of New Animal Drug
Evaluation, Center for Veterinary Medicine.
[FR Doc. 05–24270 Filed 12–19–05; 8:45 am]
§ 510.600 Names, addresses, and drug
labeler codes of sponsors of approved
applications.
BILLING CODE 4160–01–S
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DEPARTMENT OF VETERANS
AFFAIRS
*
*
(c) * * *
(1) * * *
*
*
Firm name and address
*
*
*
Pharmaceutical Ventures,
Ltd., P.O. Box D1400,
Pomona, NY 10970
*
*
*
Drug labeler
code
*
RIN 2900–AM32
*
Use of Diagnostic Code Numbers;
Schedule of Ratings-Neurological
Conditions and Convulsive Disorders
*
*
AGENCY:
ACTION:
Drug labeler
code
*
050057
38 CFR Part 4
*
050057
(2) * * *
*
*
Firm name and address
*
*
*
Pharmaceutical Ventures,
Ltd., P.O. Box D1400,
Pomona, NY 10970
*
*
*
3. The authority citation for 21 CFR
part 520 continues to read as follows:
I
Authority: 21 U.S.C. 360b.
4. Revise § 520.390b to read as
follows:
I
Chloramphenicol capsules.
(a) Specifications. Each capsule
contains 50, 100, 250, or 500 milligrams
(mg) chloramphenicol.
(b) Sponsors. See sponsors in
§ 510.600(c) of this chapter for use as in
paragraph (d) of this section.
(1) Nos. 000069, 000185, and 050057
for capsules containing 50, 100, 250, or
500 mg chloramphenicol.
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Department of Veterans Affairs.
Final rule.
SUMMARY: This document amends the
Department of Veterans Affairs (VA)
Schedule for Rating Disabilities by
updating references to diagnostic codes
in two regulations. These amendments
are necessary to correct outdated
references in the Schedule for Rating
Disabilities.
DATES:
PART 520—ORAL DOSAGE FORM
NEW ANIMAL DRUGS
§ 520.390b
List of Subjects
VerDate Aug<31>2005
Therefore, under the Federal Food,
Drug, and Cosmetic Act and under
authority delegated to the Commissioner
of Food and Drugs and redelegated to
the Center for Veterinary Medicine, 21
CFR parts 510 and 520 are amended as
follows:
I
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Effective Date: December 20,
2005.
FOR FURTHER INFORMATION CONTACT:
Maya Ferrandino, Consultant,
Compensation and Pension Service,
Policy and Regulations Staff, Veterans
Benefits Administration, 810 Vermont
Avenue, NW., Washington, DC 20420,
(202) 273–7211.
SUPPLEMENTARY INFORMATION: VA’s
Schedule for Rating Disabilities
includes criteria for evaluating
disabilities by analogy where there is no
specific diagnostic code for the
disability being evaluated. In 38 CFR
4.27 and 38 CFR 4.124a, the rating
criteria reference examples of diseases
that can be rated by analogy to certain
specified diagnostic odes. Two of the
E:\FR\FM\20DER1.SGM
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Federal Register / Vol. 70, No. 243 / Tuesday, December 20, 2005 / Rules and Regulations
diagnostic codes listed in 38 CFR 4.27
and 4.124a, for rheumatoid (atrophic)
arthritis and for dementia, are outdated
due to changes to the diagnostic criteria
for evaluating these diseases. Therefore,
we are amending 38 CFR 4.27 and
4.124a to replace outdated references
with the current diagnostic codes for
ankylosing spondylitis, a disability
similar to rheumatoid arthritis, and for
dementia.
Section 4.27, Use of diagnostic code
numbers, includes as an example:
‘‘Thus, rheumatoid (atrophic) arthritis
rated as ankylosis of the lumbar spine
should be coded 5002–5289.’’ However,
Diagnostic Code 5289 was removed
from 38 CFR 4.71a, Schedule of ratingsmusculoskeletal system, by a
rulemaking published on August 27,
2003, at 68 FR 51454. Therefore, the
reference to 5289 for ankylosis of the
lumbar spine is outdated. We will
replace the outdated reference to
Diagnostic Code 5289 with the current
Diagnostic Code for ankylosing
spondylitis, 5240, which is a disability
similar to rheumatoid arthritis.
Similarly, in § 4.124a, Schedule of
ratings-neurological conditions and
convulsive disorders, the paragraph
discussing Mental Disorders in
Epilepsies which appears after
Diagnostic Code 8914 includes
references to Diagnostic Codes 9304 and
9307 for dementia: ‘‘(e.g., 9304 or
9307)’’ and ‘‘(e.g., Diagnostic Code 9304
or 9307)’’. However, Diagnostic Code
9307 was removed by a rulemaking
published on October 8, 1996, at 61 FR
52695. Therefore, the reference to
Diagnostic Code 9307 currently in 38
CFR 4.124a is outdated. We will remove
the reference to Diagnostic Code 9307
and insert a reference to Diagnostic
Code 9326, which replaced Diagnostic
Code 9307.
Administrative Procedures Act
This final rule merely replaces
inaccurate examples and does not alter
the content of the regulations.
Accordingly, there is a basis for
dispensing with prior notice and
comment and the delayed effective date
provisions of 5 U.S.C. 553.
Paperwork Reduction Act
This document contains no provisions
constituting a collection of information
under the Paperwork Reduction Act (44
U.S.C. 3501–3521).
Regulatory Flexibility Act
Because no notice of proposed
rulemaking is required in connection
with the adoption of this final rule, no
regulatory flexibility analysis is required
under the Regulatory Flexibility Act (5
VerDate Aug<31>2005
16:09 Dec 19, 2005
Jkt 208001
75399
U.S.C. 601–612). Even so, the Secretary
hereby certifies that this final rule will
not have a significant economic impact
on a substantial number of small entities
as they are defined in the Regulatory
Flexibility Act.
ENVIRONMENTAL PROTECTION
AGENCY
Unfunded Mandates
Approval and Promulgation of
Implementation Plans and Operating
Permits Program; State of Iowa
The Unfunded Mandates Reform Act
of 1995 requires, at 2 U.S.C. 1532, that
agencies prepare an assessment of
anticipated costs and benefits before
issuing any rule that may result in the
expenditure by State, local, and tribal
governments, in the aggregate, or by the
private sector, of $100 million or more
(adjusted annually for inflation) in any
year. This final rule would have no such
effect on State, local, and tribal
governments, or on the private sector.
Catalog of Federal Domestic Assistance
Numbers: The Catalog of Federal Domestic
Assistance program numbers and titles for
this proposal are 64.104, Pension for NonService-Connected Disability for Veterans,
and 64.109, Veterans Compensation for
Service-Connected Disability.
List of Subjects in 38 CFR Part 4
Disability benefits, Pensions,
Veterans.
Approved: December 14, 2005.
Gordon H. Mansfield,
Deputy Secretary of Veterans Affairs.
For the reasons set out in the
preamble, 38 CFR part 4 is amended as
set forth below:
I
PART 4—SCHEDULE FOR RATING
DISABILITIES
1. The authority citation for part 4
continues to read as follows:
I
Authority: 38 U.S.C. 1155, unless
otherwise noted.
§ 4.27
[Amended]
2. Amend § 4.27 by removing ‘‘5002–
5289’’ and adding, in its place, ‘‘5002–
5240’’.
I
§ 4.124a
[Amended]
3. Amend § 4.124a following the
undesignated center heading ‘‘The
Epilepsies’’ at the conclusion of the
table in the undesignated paragraph
‘‘Mental Disorders in Epilepsies’’
remove ‘‘9307’’ and add in its place
‘‘9326’’.
I
[FR Doc. 05–24272 Filed 12–19–05; 8:45 am]
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40 CFR Parts 52 and 70
[EPA–R07–OAR–2005–IA–0006; FRL–8010–
9]
Environmental Protection
Agency (EPA).
ACTION: Direct final rule.
AGENCY:
SUMMARY: EPA is approving the State
Implementation Plan (SIP) revision
submitted by the state of Iowa. This
revision includes the general
rulemaking that Iowa completes for the
purpose of updating and clarifying
various rules, and making other minor
revisions as generally described in this
document. EPA is also proposing
approval of revisions to the Iowa
Operating Permits Program for the
purpose of updating and clarifying
various rules included in the general
rulemaking. These revisions add new
definitions, as well as an administrative
correction to a previously submitted
rule. Approval of these revisions will
ensure consistency between the state
and Federally-approved rules, and
ensure Federal enforceability of the
State’s revised air program rules.
DATES: This direct final rule will be
effective February 21, 2006, without
further notice, unless EPA receives
adverse comment by January 19, 2006.
If adverse comment is received, EPA
will publish a timely withdrawal of the
direct final rule in the Federal Register
informing the public that the rule will
not take effect.
ADDRESSES: Submit your comments,
identified by Docket ID No. EPA–R07–
OAR–2005–IA–0006, by one of the
following methods:
1. https://www.regulations.gov. Follow
the on-line instructions for submitting
comments.
2. E-mail: Heather Hamilton at
hamilton.heather@epa.gov.
3. Mail: Heather Hamilton,
Environmental Protection Agency, Air
Planning and Development Branch, 901
North 5th Street, Kansas City, Kansas
66101.
4. Hand Delivery or Courier. Deliver
your comments to Heather Hamilton,
Environmental Protection Agency, Air
Planning and Development Branch, 901
North 5th Street, Kansas City, Kansas
66101.
Instructions: Direct your comments to
Docket ID No. EPA–R07–OAR–2005–
IA–0006. EPA’s policy is that all
comments received will be included in
E:\FR\FM\20DER1.SGM
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Agencies
[Federal Register Volume 70, Number 243 (Tuesday, December 20, 2005)]
[Rules and Regulations]
[Pages 75398-75399]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 05-24272]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF VETERANS AFFAIRS
38 CFR Part 4
RIN 2900-AM32
Use of Diagnostic Code Numbers; Schedule of Ratings-Neurological
Conditions and Convulsive Disorders
AGENCY: Department of Veterans Affairs.
ACTION: Final rule.
-----------------------------------------------------------------------
SUMMARY: This document amends the Department of Veterans Affairs (VA)
Schedule for Rating Disabilities by updating references to diagnostic
codes in two regulations. These amendments are necessary to correct
outdated references in the Schedule for Rating Disabilities.
DATES: Effective Date: December 20, 2005.
FOR FURTHER INFORMATION CONTACT: Maya Ferrandino, Consultant,
Compensation and Pension Service, Policy and Regulations Staff,
Veterans Benefits Administration, 810 Vermont Avenue, NW., Washington,
DC 20420, (202) 273-7211.
SUPPLEMENTARY INFORMATION: VA's Schedule for Rating Disabilities
includes criteria for evaluating disabilities by analogy where there is
no specific diagnostic code for the disability being evaluated. In 38
CFR 4.27 and 38 CFR 4.124a, the rating criteria reference examples of
diseases that can be rated by analogy to certain specified diagnostic
odes. Two of the
[[Page 75399]]
diagnostic codes listed in 38 CFR 4.27 and 4.124a, for rheumatoid
(atrophic) arthritis and for dementia, are outdated due to changes to
the diagnostic criteria for evaluating these diseases. Therefore, we
are amending 38 CFR 4.27 and 4.124a to replace outdated references with
the current diagnostic codes for ankylosing spondylitis, a disability
similar to rheumatoid arthritis, and for dementia.
Section 4.27, Use of diagnostic code numbers, includes as an
example: ``Thus, rheumatoid (atrophic) arthritis rated as ankylosis of
the lumbar spine should be coded 5002-5289.'' However, Diagnostic Code
5289 was removed from 38 CFR 4.71a, Schedule of ratings-musculoskeletal
system, by a rulemaking published on August 27, 2003, at 68 FR 51454.
Therefore, the reference to 5289 for ankylosis of the lumbar spine is
outdated. We will replace the outdated reference to Diagnostic Code
5289 with the current Diagnostic Code for ankylosing spondylitis, 5240,
which is a disability similar to rheumatoid arthritis.
Similarly, in Sec. 4.124a, Schedule of ratings-neurological
conditions and convulsive disorders, the paragraph discussing Mental
Disorders in Epilepsies which appears after Diagnostic Code 8914
includes references to Diagnostic Codes 9304 and 9307 for dementia:
``(e.g., 9304 or 9307)'' and ``(e.g., Diagnostic Code 9304 or 9307)''.
However, Diagnostic Code 9307 was removed by a rulemaking published on
October 8, 1996, at 61 FR 52695. Therefore, the reference to Diagnostic
Code 9307 currently in 38 CFR 4.124a is outdated. We will remove the
reference to Diagnostic Code 9307 and insert a reference to Diagnostic
Code 9326, which replaced Diagnostic Code 9307.
Administrative Procedures Act
This final rule merely replaces inaccurate examples and does not
alter the content of the regulations. Accordingly, there is a basis for
dispensing with prior notice and comment and the delayed effective date
provisions of 5 U.S.C. 553.
Paperwork Reduction Act
This document contains no provisions constituting a collection of
information under the Paperwork Reduction Act (44 U.S.C. 3501-3521).
Regulatory Flexibility Act
Because no notice of proposed rulemaking is required in connection
with the adoption of this final rule, no regulatory flexibility
analysis is required under the Regulatory Flexibility Act (5 U.S.C.
601-612). Even so, the Secretary hereby certifies that this final rule
will not have a significant economic impact on a substantial number of
small entities as they are defined in the Regulatory Flexibility Act.
Unfunded Mandates
The Unfunded Mandates Reform Act of 1995 requires, at 2 U.S.C.
1532, that agencies prepare an assessment of anticipated costs and
benefits before issuing any rule that may result in the expenditure by
State, local, and tribal governments, in the aggregate, or by the
private sector, of $100 million or more (adjusted annually for
inflation) in any year. This final rule would have no such effect on
State, local, and tribal governments, or on the private sector.
Catalog of Federal Domestic Assistance Numbers: The Catalog of
Federal Domestic Assistance program numbers and titles for this
proposal are 64.104, Pension for Non-Service-Connected Disability
for Veterans, and 64.109, Veterans Compensation for Service-
Connected Disability.
List of Subjects in 38 CFR Part 4
Disability benefits, Pensions, Veterans.
Approved: December 14, 2005.
Gordon H. Mansfield,
Deputy Secretary of Veterans Affairs.
0
For the reasons set out in the preamble, 38 CFR part 4 is amended as
set forth below:
PART 4--SCHEDULE FOR RATING DISABILITIES
0
1. The authority citation for part 4 continues to read as follows:
Authority: 38 U.S.C. 1155, unless otherwise noted.
Sec. 4.27 [Amended]
0
2. Amend Sec. 4.27 by removing ``5002-5289'' and adding, in its place,
``5002-5240''.
Sec. 4.124a [Amended]
0
3. Amend Sec. 4.124a following the undesignated center heading ``The
Epilepsies'' at the conclusion of the table in the undesignated
paragraph ``Mental Disorders in Epilepsies'' remove ``9307'' and add in
its place ``9326''.
[FR Doc. 05-24272 Filed 12-19-05; 8:45 am]
BILLING CODE 8320-01-P